The U.S. flu scene & peramivir
While we wipe away yet another tear for the never-ending demise of Brett Favre, there is some good news emanating from CDC:
Summary of Weekly FluView (http://www.cdc.gov/flu/weekly/summary.htm)
“…….Visits to doctors for influenza-like illness (ILI) continue to be low nationally. All 10 U.S. regions continue to report ILI below region-specific baseline levels; however, ILI levels are rising in Region 4 (AL, FL, GA, KY, MS, NC, SC, and TN). One state (Georgia) reported moderate ILI activity for the first time this season.
The proportion of deaths attributed to pneumonia and influenza (P&I) based on the 122 Cities Mortality Reporting System increased over last week but is still within the range of what is expected for this time of year.
No pediatric deaths were reported for the week.
No states reported widespread or regional influenza activity. Puerto Rico and four states (Georgia, Mississippi, Oklahoma and Pennsylvania) reported local influenza. Sporadic influenza activity was reported by the District of Columbia and 34 states. Guam and 12 states reported no activity, and the U.S. Virgin Islands did not report…….”

Meanwhile, IV peramivir seems to be an effective therapeutic agent for seasonal flu. The study looked at a single intravenous dose of the neuraminidase inhibitor. The drug reduced the duration of influenza (mostly H1N1 strain) symptoms when compared to placebo and was well tolerated among 300 healthy outpatients with confirmed flu. No serious side effects were noted. The study involved healthy subjects, however. So we really don’t know what the result would be for really sick or chronically compromised flu patients. Link to the abstract: http://aac.asm.org/cgi/content/abstract/54/11/4568.
This entry was posted
on
Tuesday, November 23rd, 2010 at
1:40 am and is filed under
Uncategorized.
You can follow any responses to this entry through the
RSS 2.0 feed.
You can leave a response, or trackback from your own site.